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Ichiro Akiguchi Selected Research

14-3-3 Proteins (14-3-3 Protein)

3/2006Upregulated expression of 14-3-3 proteins in astrocytes from human cerebrovascular ischemic lesions.
8/200514-3-3 proteins in Lewy body-like hyaline inclusions in a patient with familial amyotrophic lateral sclerosis with a two-base pair deletion in the Cu/Zn superoxide dismutase (SOD1) gene.
12/200414-3-3 proteins in Lewy body-like hyaline inclusions in patients with sporadic amyotrophic lateral sclerosis.
10/2004Enhanced expression of 14-3-3 proteins in reactive astrocytes in Creutzfeldt-Jakob disease brains.
2/2004Increased 14-3-3 immunoreactivity in glial elements in patients with multiple sclerosis.
12/2002Accumulation of 14-3-3 proteins in glial cytoplasmic inclusions in multiple system atrophy.
3/200214-3-3 proteins in Lewy bodies in Parkinson disease and diffuse Lewy body disease brains.

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Ichiro Akiguchi Research Topics

Disease

6Alzheimer Disease (Alzheimer's Disease)
01/2015 - 10/2004
5Vascular Dementia (Subcortical Arteriosclerotic Encephalopathy)
05/2012 - 11/2003
4Cognitive Dysfunction
01/2015 - 01/2002
4Multiple System Atrophy
10/2008 - 12/2002
4Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
08/2005 - 02/2002
3Dementia (Dementias)
10/2008 - 06/2003
3Parkinson Disease (Parkinson's Disease)
03/2007 - 03/2002
3Brain Ischemia (Cerebral Ischemia)
03/2006 - 12/2002
2Neurodegenerative Diseases (Neurodegenerative Disease)
10/2008 - 06/2003
2Synucleinopathies
10/2008 - 06/2003
1Atrophy
08/2017
1Intracranial Thrombosis (Cerebral Thrombosis)
03/2006
1Intracranial Embolism
03/2006
1Gliosis
03/2006
1Lacunar Stroke
03/2006
1Acquired CJD
10/2004
1Creutzfeldt-Jakob Syndrome (Creutzfeldt-Jakob Disease)
10/2004
1Stroke (Strokes)
06/2004
1Infarction (Infarctions)
06/2004
1Cerebral Hemorrhage
06/2004
1Progressive Multifocal Leukoencephalopathy
02/2004
1Multiple Sclerosis
02/2004
1Miyoshi myopathy
04/2003
1Peripheral Nervous System Diseases (PNS Diseases)
03/2003
1Lewy Body Disease (Lewy Body Dementia)
03/2002
1Guillain-Barre Syndrome
02/2002
1Experimental Autoimmune Neuritis
02/2002
1Polyneuropathies (Polyneuropathy)
02/2002
1Demyelinating Diseases (Demyelinating Disease)
01/2002

Drug/Important Bio-Agent (IBA)

714-3-3 Proteins (14-3-3 Protein)IBA
03/2006 - 03/2002
5Protons (Proton)IBA
01/2015 - 01/2008
4Proteins (Proteins, Gene)FDA Link
03/2006 - 01/2002
3alpha-SynucleinIBA
10/2008 - 06/2003
2Peptides (Polypeptides)IBA
06/2004 - 01/2002
1lipopigmentsIBA
08/2017
1N-acetylaspartate (N-acetyl aspartate)IBA
03/2012
1Inositol (Myoinositol)IBA
03/2012
1Heat-Shock Proteins (Heat-Shock Protein)IBA
03/2006
1Formaldehyde (Formol)FDA Link
03/2006
1ParaffinIBA
03/2006
1Superoxide Dismutase-1IBA
08/2005
1CeramidesIBA
10/2004
1Indicators and Reagents (Reagents)IBA
06/2004
1Horseradish PeroxidaseIBA
06/2004
1Amyloid (Amyloid Fibrils)IBA
06/2004
1ibudilastIBA
11/2003
1GTP-Binding Proteins (G-Protein)IBA
06/2003
1Creatine Kinase (Creatine Phosphokinase)IBA
04/2003
1Transcription Factors (Transcription Factor)IBA
03/2003
1Immunoglobulin M (IgM)IBA
03/2003
1GangliosidesIBA
03/2003
1Prostaglandin-Endoperoxide Synthases (Cyclooxygenase)IBA
12/2002
1Arachidonate 5-Lipoxygenase (5 Lipoxygenase)IBA
12/2002
1Cyclooxygenase 2 (Cyclooxygenase-2)IBA
02/2002
1Celecoxib (Celebrex)FDA Link
02/2002
1Cyclooxygenase 2 Inhibitors (COX-2 Inhibitors)IBA
02/2002
1Meloxicam (Mobic)FDA LinkGeneric
02/2002
1Amyloid beta-PeptidesIBA
01/2002
1Chromogranin AIBA
01/2002

Therapy/Procedure

1Therapeutics
11/2006
1Ligation
01/2002